PROGRAM
Wednesday, September 30
Arrival
Mixer 5:00-6:30 PM, Swope
Dinner 6:30-7:30
Introduction 7:30, Lillie Auditorium
Jim Coffman (MDIBL): Welcome and opening remarks
Plenary Session I- The GRN in Development and Evolution
7:45-9:15, Lillie Auditorium Chair: Paola Oliveri
Eric Davidson (Caltech): Gene regulatory networks
Joel Smith (Caltech): Regulative recovery in the sea urchin embryo, and the stabilizing role of fail-safe gene network wiring
Greg Wray (Duke): Microevolutionary and developmental dynamics of a gene regulatory network
Social 9:30-11:00, Swope
Thursday, October 1
Breakfast 7:30-8:30 AM
Plenary Session II- Mechanisms of Cell Fate Specification
8:30-12:00, Lillie Auditorium Chair: Shunsuke Yaguchi
Isabelle Peter (Caltech): Different modes of endoderm specification: insights from a network
Enhu Li (Caltech): Solving the sea urchin ectodermal gene regulatory network
Lynne Angerer (NIH): Development of the animal pole domain
Coffee Break 10:00-10:30
Smadar Ben-Tabou de-Leon (Caltech): foxa cis-regulation: a spatio-temporal tale
Alexandra Saudemont (Villefranche-sur-Mer): Deciphering the dorsal-ventral ectoderm gene regulatory network in Paracentrotus lividus
Chuck Ettensohn (Carnegie Mellon): Normal and regulative deployment of the skeletogenic gene regulatory network
Lunch 12:00-1:00 PM
Emerging Topics I- Genomics: New Technology and Computational Approaches
1:15-3:20, Lillie Auditorium Chair: Andrew Cameron
David Garfield (Duke): Natural selection in Strongylocentrotid sea urchins: the view from the genome
Albert Poustka (Max Planck, Berlin): De novo S. purpuratus embryo transcriptome assembly from Solexa reads and comparison to gene predictions from the genome
Bill Longabaugh (Institute for Systems Biology): BioTapestry: recent enhancements support the modeling and presentation of high-level network features
Sorin Istrail (Brown): Report on the CYRENE Project: A cis-Lexicon containing the cis-regulatory architecture of 300 regulatory genes
Autumn Yuan (Caltech): SpBase: the sea urchin genome database and web site
Coffee Break 3:20-3:45
Concurrent Session I- Developmental Physiology
3:45-5:45, Lillie Auditorium Chair: Donal Manahan
Andrea Bodnar (Bermuda Institute of Ocean Sciences): The secret to longevity: sea urchins as models for aging research
Amro Hamdoun (Scripps Institution of Oceanography, UCSD): Throwing switches: cell biological regulation of multidrug efflux transport in development
Bryan Cole (Stanford): Costs, benefits, and developmental expression of multidrug transporter proteins in S. purpuratus embryos
Tony De Tomaso (U. California Santa Barbara): Early lineage specification and characterization of adult stem cells in the colonial ascidian, Botryllus schlosseri
Sam Dupont (U. Gothenburg): Impact of ocean acidification on echinoderm developmental rate and larval physiology - consequences for experimental design
Hideki Katow (Tohoku U.): Dopaminergic preneural regulatory mechanism of embryonic swimming activity
Andrew Juurinen (U. Victoria): Axon pathfinding: netrin and its receptors
Concurrent Session II- Regulation of Gene Expression
3:45-5:45, Speck Auditorium Chair: David McClay
Patrick Cormier (Station Biologique de Roscoff): eIF4E-binding proteins are differentially modified after ammonia versus intracellular calcium activation of sea urchin unfertilized eggs
Jia Song (Brown): Regulatory roles of small RNAs in early development
Eric Gustafson (Brown): Gustavus directs Vasa accumulation selectively in multipotent cells during embryogenesis
Magali Quirin (Villefranche-sur-Mer): Control of nodal expression and dorso-ventral polarity by maternal transcription factors downstream of the MAPK pathway
ChiehFu Peng (U. Miami): Establishment and maintenance of the Dishevelled vegetal cortical domain in the sea urchin egg
Tara Sharma (Carnegie Mellon): Activation of the micromere-PMC gene regulatory network
Ho Kyung Rho (Duke): The role and regulation of foxN2/3 in the skeletogenic cells during sea urchin development
Poster Session 5:45-6:30, Swope
Dinner 6:30-7:30
Plenary Session III- Cellular and Developmental Physiology
7:30-9:50, Lillie Auditorium Chair: Amro Hamdoun
Michael Whitaker (Newcastle U.): Cdk2/cyclinE dependent DNA synthesis initiation after fertilization in sea urchin eggs is mediated by calcium-triggered ERK1 activation.
Gary Wessel (Brown): Cell surface changes in the egg at fertilization
Brad Shuster (New Mexico State U.): Defining the cleavage plane in the early sea urchin embryo
David Burgess (Boston College): Sea urchin zygotes exhibit cell polarity upon cleavage
Donal Manahan (U. Southern California): Molecular physiology of amino acid transporters during sea urchin development
Poster Session 10:00-11:00, Swope
Friday, October 2
Breakfast 7:30-8:30 AM
Plenary Session IV- Cell Signaling and Morphogenesis
8:30-12:00, Lillie Auditorium Chair: Jenifer Croce
Jenifer Croce (Villefranche-sur-Mer): Endomesoderm diversification during sea urchin embryogenesis
David McClay (Duke): Preparation for morphogenesis
Thierry Lepage (Villefranche-sur-Mer): Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-Chordin signaling network
Coffee Break 10:00-10:30
Nadine Peyriéras (CNRS, Paris): Reconstructing the cell lineage tree of Paracentrotus lividus as a framework for multiscale dynamics analysis
Mat Barnet (Caltech): In vivo time-lapse imaging of sea urchin development: watching gastrulation as it happens
Robert Burke (U. Victoria): Neural development
Lunch 12:00-1:00 PM
Emerging Topics II: Evolution of Development
1:15-3:20, Lillie Auditorium Chair: Athula Wikramanayake
Feng Gao (Caltech): Comparative study of delta gene cis-regulatory modules across 500 million years of evolution
Eric Roettinger (U. Hawaii): Investigating the role of the Nodal signaling pathway in a indirect developing hemichordate, Ptychodera flava
Koji Akasaka (U. Tokyo): Gene expression involved in patterning along the anterior-posterior axis in crinoid (Oxycomanthus japonicus) development
Kristen Yankura (Carnegie Mellon): Complex regulatory patterning of sea star embryonic ectoderm supports a larval origin of the deuterostomes
Coffee Break 3:20-3:45
Concurrent Session III: Functional Genomics and Gene Regulation
3:45-5:45, Lillie Auditorium Chair: Ina Arnone
Cynthia Messier-Solek (U. Toronto): Role of Sp-Gatac and Sp-Scl in specification of mesodermal cells in the sea urchin embryo
Paola Oliveri (U. College London): Analysis of the cis-regulatory system of the tbrain gene beyond GRN validation
Celina Juliano (Brown): Nanos is required to maintain the fate of the small micromere lineage
Mamiko Yajima (Brown): Vasa is essential for cell cycle progression
Ina Arnone (Stazione Zoologica Anton Dohrn): Gene regulation and organogenesis: evolution of digestive functions
Andy Ransick (Caltech): Modulation of Spgcm transcriptional regulation in the early mesenchyme blastula
Concurrent Session IV: Developmental Biochemistry and Cell Biology
3:45-5:45, Speck Auditorium Chair: Valeria Matranga
Brigitte Ciapa (UMR CNRS, Paris): Mechanisms of cell death in unfertilized sea urchin eggs
Julia Morales (Station Biologique de Roscoff): Translational control during apoptosis in sea urchin embryos
Antoine Aze (Banyuls-sur-mer): An unexpected cell cycle arrest with assembled pre-RC in unfertilized sea urchin eggs
Sandip Patel (U. College London): Molecular aspects of calcium signaling in the sea urchin
Richard Byrne (Cancer Research UK): Spatial and temporal regulation of phosphoinositide metabolism regulates nuclear envelope formation
Valeria Matranga (IBIM, CNR Palermo): Skeleton growth inhibition in sea urchin embryos Paracentrotus lividus after manganese exposure
Fred Wilt (Berkeley): Matrix and mineral in endoskeleton form and function
Poster Session 5:45-6:30, Swope
Dinner 6:30-7:30
Plenary Session V- Larval and Adult Development
7:30-9:30, Lillie Auditorium Chair: Jonathan Rast
Detlev Arendt (EMBL Heidelberg): A brain expression atlas of the Platynereis larval nervous system
Jonathan Rast (U. Toronto): Immunity in the feeding sea urchin larva
Judy Venuti (LSU HSC New Orleans): Constructing the sea urchin tube foot nervous system
Diane Adams (NIH): Dopamine mediates ectodermal-mesenchymal signaling underlying a developmental response to food availability
Poster Session 9:45-11:00, Swope
Saturday, October 3
Breakfast 7:30-8:30 AM
Plenary Session VI- Genomic and Developmental Evolution
8:30-12:00, Lillie Auditorium Chair: Veronica Hinman
Mark Martindale (U. Hawaii): An embryologist’s bottoms up view of bilaterian body plan evolution
Athula Wikramanayake (U. Miami): The evolution of gastrulation: insights from sea urchins and sea anemones
Veronica Hinman (Carnegie Mellon): Comparison of GRN architectures for mesoderm specification in sea urchins and sea stars
Coffee Break 10:00-10:30
Andy Cameron (Caltech): The evolution of cis-regulatory modules
Brad Davidson (U. Arizona): Cell fate specification in tunicate heart development and chordate heart evolution
Mike Thorndyke (Royal Swedish Academy): Near future ocean acidification increases growth rate of the lecithotrophic larvae and juvenile of the seastar Crossaster papposus
Lunch 12:00-1:00 PM
Emerging Topics III– The Regulatory Genome and New Approaches
1:15-3:20, Lillie Auditorium Chair: Isabelle Peter
Julius Barsi (Caltech): Regulatory gene interactions that drive development of the neurogenic ciliated band in the sea urchin embryo
Qiang Tu (Caltech): cis-Regulatory analysis of SpTgif
Cyndi Bradham (Boston U.): Pantropic retroviruses: a new rransduction tool for sea urchin embryos
Yi-Hsien Su (Academia Sinica Taiwan): A top-down approach to identify unknown signaling ligands predicted from GRN analysis
Jongmin Nam (Caltech): A novel experimental method for the multiplex and quantitative measurement of cis-regulatory module activity in vivo
Coffee Break 3:20-3:45
Concurrent Session V- Advances and Opportunities in Undergraduate Research and Education
3:45-5:45, Lillie Auditorium Chair: Peggy Peeler
Jason Hodin (Stanford): Virtual Urchin as a community-wide educational outreach tool: a proposal
Panel Discussion: Careers in Undergraduate Teaching and Research – Rewards and Challenges
Peggy Peeler (Susquehanna U.), John Henson (Dickinson College), Laura Romano (Denison College), Eric Ingersol (Penn State Abington), Rachel Fink (Mount Holyoke), and Carol Burdsal (Tulane, NSF)
Concurrent Session VI- Cell Signaling and Fate
3:45-5:45, Speck Auditorium Chair: Jim Coffman
Ryan Range (NIH): Wnt antagonists regulate the animal pole domain boundary in the sea urchin embryo
Karl Bergeron (Simon Fraser U.): Sulfated glycosaminoglycans modulate Nodal signaling in the urchin embryo
Katherine Buckley (U. Toronto): The sea urchin toll-like receptor gene family represents a novel form of immunity
Harald Hausen (U. Bonn): Light matters- Identification of a complex photoreceptor system in sea urchins and starfish
Shunsuke Yaguchi (Shimoda Marine Research Center): A zinc finger protein, Fez, downstream of FoxQ2, influences development of serotonergic neurons and the size of the animal plate ectoderm in the sea urchin embryo
Homayoun Vaziri (U. Toronto): Telomeres and telomerase reverse transcriptase genes of Strongylocentrotus purpuratus
Business Meeting 6:00-6:30, Lillie Auditorium
Social 6:30, Swope
Lobster Banquet 7:30
Sunday, October 4
Breakfast 7:30-8:30 AM
Departure
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